May 18, 2017 
40 videos 
European Network to Cure ALS (ENCALS), Ljubljana 2017
Amyotrophic lateral sclerosis (ALS) is a devastating disease that is still lacking an effective cure. In recent year, research advances offer hope that ALS will eventually become a preventable and treatable disease. Patients, researchers and clinicians worldwide have joined forces in various international projects to make progress towards this goal. European Network to Cure ALS (ENCALS) is a network of ALS centres in Europe that supports such collaborations. 2017 is an exciting year for the ALS community since positive clinical drug trials are promising new treatments after more than two decades.
The ENCALS Meeting 2017 was hosted by the Ljubljana ALS Centre and the Slovenian Society of Clinical Neurophysiology. In three days, a series of plenary lectures, thematic sessions and poster resentations brought together international researchers and clinicians to discuss the advances in research and clinical care.
Opening Session
Opening session
Jul 21, 2017 840 views
Keynotes
Protein-RNA complexes & ALS: insights from iCLIP
Jul 21, 2017 1002 views
Masitinib as an add-on therapy to riluzole is beneficial in the treatment of amy...
Jul 21, 2017 3119 views
Invited Talks
Cognitive and behavioural symptoms in ALS: why are they there and how to assess ...
Jul 21, 2017 797 views
The panorama of ALS genomics
Jul 21, 2017 930 views
Tracking ALS progression using neuroimaging
Jul 21, 2017 941 views
Gene expression profiling in ALS: past, present and future
Jul 21, 2017 890 views
ENCALS Young Investigator Award 2017
Clinical, pathological and molecular characterisation of C9orf72-ALS leads to id...
Sep 22, 2017 1182 views
Session 1: Therapy
Intraspinal injection of human mesenchymal stromal cells in SOD1G93A ALS mice
Jul 21, 2017 972 views
Bringing gene therapy based SOD1 silencing towards human trials: A highly effica...
Jul 21, 2017 788 views
Session 2: Clinical & Epidemiology
The time of the ALSFRS-R to decrease to 50% (D50) in a sigmoidal decay model suf...
Jul 21, 2017 1588 views
Global ALS/MND "big data" collaboration environment in a post-PRO-ACT era
Jul 21, 2017 927 views
Euro-MOTOR: A multi-centre population-based case-control study of metals and sol...
Jul 21, 2017 849 views
The role of pre-morbid diabetes on developing amyotrophic lateral sclerosis
Jul 21, 2017 933 views
AB Science Satellite Meeting
Masitinib for the treatment of amyotrophic lateral sclerosis (ALS): preclinical ...
Jul 21, 2017 1233 views
Session 3: Genetics A
Serum microRNA-profiles indicate a role of Fragile-X-related proteins for ALS
Jul 21, 2017 766 views
Whole genome sequencing as tool to unravel rare variants associated with ALS sur...
Jul 21, 2017 809 views
The Project MinE data browser: bringing whole-genome sequencing data in ALS to r...
Jul 21, 2017 842 views
Discovery of microRNA gene mutations in ALS patient genomes
Jul 21, 2017 822 views
Session 4: Genetics B
ATXN1: expanding the spectrum of polyglutamine repeats in ALS
Jul 21, 2017 1411 views
Integrating copy-number analysis with structural-variation detection in 50 ALS p...
Jul 21, 2017 821 views
A high throughput gene, environment and epigenetics database and analysis system...
Jul 21, 2017 879 views
MicroRNAs analysis of patient-derived iPSCs as molecular therapy for ALS
Jul 21, 2017 941 views
Session 5: Cognition & Imaging
Assessing behaviour in ALS: the importance of using disease-specific tools
Jul 21, 2017 917 views
Hypothalamic atrophy correlates with onset of disease-defining symptoms in patie...
Jul 21, 2017 789 views
A PET/CT approach to spinal cord metabolism
Jul 21, 2017 920 views
The brief Dimensional Apathy Scale (b-DAS): Mokken analysis and scale reduction
Jul 21, 2017 1191 views
Session 6: Disease mechanisms A
Dynamic polymerization of TDP-43 in health and disease
Jul 21, 2017 966 views
Developing vertebrate models to highlight the functional relevance of Nefl and m...
Jul 21, 2017 820 views
Phase separation of C9orf 72 dipeptide repeats perturbs stress granule dynamics
Jul 21, 2017 688 views
Role of FUS in post synaptic neuromuscular junction differentiation
Jul 21, 2017 1109 views
Session 7: Disease mechanisms B
Two G-quadruplex structures adopted by oligonucleotide model of ALS and FTD link...
Jul 21, 2017 854 views
Deciphering the function and mechanisms of C9ORF72 in ALS
Jul 21, 2017 885 views
The role of valosin containing protein (VCP) in the clearance of toxic misfolded...
Jul 21, 2017 911 views
Live imaging of RNA dynamics for genetic forms of amyotrophic lateral sclerosis ...
Jul 21, 2017 916 views
Session 8: Disease mechanisms C
Secretion of toxic exosomes by muscle cells of ALS patients: role in ALS pathoge...
Jul 21, 2017 1142 views
RNA toxicity in a zebrafish model for C9orf 72 ALS is abrogated by Pur-alpha and...
Jul 21, 2017 960 views
C9orf 72 interacts with coilin and influences Cajal body dynamics and splicing
Jul 21, 2017 1021 views
Intranuclear (G4C2)n RNA foci, transcribed from C9ORF72 hexanucleotide expansio...
Jul 21, 2017 1009 views
Closing of the Meeting
Closing of the meeting
Jul 21, 2017 777 views